Short, Simple Treatment. Lasting Lung Health.

The dNerva® Lung Denervation System is novel, catheter-based system used to treat overactive airway nerves in a procedure called Targeted Lung Denervation. This first-of-its kind technology addresses underlying COPD pathophysiology to help preserve lung health.1,2

Before & After

The dNerva Difference

With less acetylcholine release, the airway smooth muscle relaxes and mucous secretion decreases moving the pulmonary system to a state of “low alert”. This has the potential to reduce exacerbation risk, improve COPD symptoms and stabilize lung function over time.

Targeted Lung Denervation

Disrupting Pulmonary Nerve Input

Targeted Lung Denervation (TLD) is a non-surgical, outpatient procedure that involves passing the specialized, dNerva Catheter through a flexible bronchoscope to complete a full circumferential ablation in the main bronchi of each lung.

The ablation permanently disrupts pulmonary nerve input to the lung to reduce the clinical consequences of neural hyperactivity.

Non-surgical, Outpatient Treatment

The Procedure

Targeted Lung Denervation

01: Position

The dNerva Catheter threads through the working channel of the bronchoscope and is positioned in the main bronchi.

02: Inflation

The conduit and balloon are inflated by circulating the coolant through the catheter which brings the electrode in contact with the airway wall.

03: Confirmation

Confirm good contact of the electrode with the airway wall and that adequate distance from the esophagus is achieved.

04: Activation

Activation of the radio-frequency energy lasts approximately 2 minutes per position. Each bronchus is treated four times to complete circumferential ablation.

First element

Thias is a description